Insights into Novel and Emerging Pipeline Therapies, Key Pharma Players, Clinical Trials, Growth Prospects, and Treatment Landscape | DelveInsight

Epilepsy Pipeline: Insights into Novel and Emerging Pipeline Therapies, Key Pharma Players, Clinical Trials, Growth Prospects, and Treatment Landscape | DelveInsight

The Epilepsy Pipeline landscape is evolving with increased insight into biological pathways and mechanisms underlying Epilepsy, leading towards more targeted therapies.

DelveInsight’s ‘Epilepsy Pipeline Insight 2021’ report offers exhaustive global coverage of available, marketed, and pipeline therapies under different phases of clinical development, key companies working to advance the pipeline space, and future growth potential of the Epilepsy pipeline domain.

Some of the essential takeaways from the Epilepsy Pipeline report:

DelveInsight’s Epilepsy Pipeline analysis depicts the space with 70+ active players working to develop 70+ pipeline therapies.
Major pharmaceutical companies are developing potential drug candidates to improve the Epilepsy treatment scenario, such as Otsuka Pharmaceutical Co. Ltd, Cerebral Therapeutics LLC, Marinus Pharmaceuticals, Xenon Pharmaceuticals, PTC Therapeutics, Eisai, Longboard Pharmaceuticals, Neurocrine Biosciences, and others.
Key Epilepsy pipeline therapies such as OPC-214870, CT-010, Ganaxolone, XEN496, Vatiquinone E-2730, LP352, NBI 827104, and others are under investigation in different phases of clinical trials.
In January 2021, Addex Therapeutics announced that its partner Janssen Pharmaceuticals had received FDA’s Investigational New Drug (IND) approval to begin a Phase IIa proof of concept study with the selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulator (PAM), JNJ-40411813 (ADX71149), in patients with Epilepsy.
In October 2020, PTC Therapeutics announced the initiation of a registration-directed Phase II/III clinical trial to evaluate vatiquinone (PTC743) in patients with mitochondrial Epilepsy, the highly morbid condition of refractory seizures in children with inherited mitochondrial disease.

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The Epilepsy pipeline report lays down detailed profiles of the pipeline assets, inactive and dormant assets, comparative analysis of clinical and non-clinical stage Epilepsy products, comprehensive assessment of driving and restraining factors, and opportunities as well as risks in the Epilepsy pipeline landscape.

Epilepsy Overview

Epilepsy is a chronic neurological disorder characterized by frequent and recurring seizures leading to unusual behavior. The primary cause of Epilepsy is not clear, but it is noted that any change in the nerve cells, neurons, and the brain resulting in abnormal signals can be the possible reason.

The most common symptom of Epilepsy includes seizures; however, additional symptoms like convulsion without fever, low consciousness, less awareness, loss of taste, smell, sight, hearing, etc., can also be present.

For further information about Epilepsy treatment and pipeline therapies, visit @ Epilepsy Pipeline Assessment

Epilepsy Pipeline Drugs
Drug Company Phase MoA RoA
OPC-214870 Otsuka Pharmaceutical Co. Ltd Phase I Antiepileptic Oral
CT-010 Cerebral Therapeutics LLC Phase II 4-aminobutyrate transaminase inhibitors Intraventricular
Ganaxolone Marinus Pharmaceuticals Phase III GABA A receptor agonists Intravenous
XEN496 Xenon Pharmaceuticals Phase III KCNQ potassium channel agonists Oral
Vatiquinone PTC Therapeutics Phase II/III NQO1 modulators Oral
E-2730 Eisai Phase II Synaptic transmission modulators Oral
NBI 827104 Neurocrine Biosciences Phase II T type calcium channel antagonists Oral

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Epilepsy Therapeutics Assessment

The Epilepsy Pipeline report proffers an integral view of the Epilepsy emerging novel therapies segregated by Stage, Product Type, Route of Administration, Molecule Type, and Mechanism of Action.

By Product Type

Mono
Combination
Mono/Combination

By Stage

Discovery
Pre-clinical
Phase I
Phase II
Phase III
Pre-registration

By Route of Administration

Subcutaneous
Intravenous
Oral
Intraventricular
Inhalation

By Molecule Type

Gene therapy
Stem cell therapy
Small molecules
Pyridines

By Mechanism of Action

4-aminobutyrate transaminase inhibitors
GABA A receptor agonists
KCNQ potassium channel agonists
NQO1 modulators
Serotonin receptor agonists
T type calcium channel antagonists

By Targets

GABA A receptor
KCNQ potassium channel
Serotonin receptor
NQO1
T type calcium channel
Synaptic transmission

Scope of the Epilepsy Pipeline Report

Coverage: Global
Major Players: Otsuka Pharmaceutical Co. Ltd, Cerebral Therapeutics LLC, Marinus Pharmaceuticals, Xenon Pharmaceuticals, PTC Therapeutics, Eisai, Longboard Pharmaceuticals, Neurocrine Biosciences, and others.
Key Epilepsy Pipeline Therapies: OPC-214870, CT-010, Ganaxolone, XEN496, Vatiquinone E-2730, LP352, NBI 827104, and others.

Dive deep into rich insights of Epilepsy novel and emerging drugs and their analysis @ Epilepsy Pipeline Emerging Novel Therapies

Table of Contents
1 Introduction
2 Executive Summary
3 Epilepsy: Overview
4 Epilepsy – Analytical Perspective In-depth Commercial Assessment
5 Pipeline Therapeutics
6 Late Stage Products (Phase III)
7 Late Stage Products (Phase II/III)
8 Mid Stage Products (Phase II)
9 Early Stage Products (Phase I)
10 Therapeutic Assessment
11 Inactive Products
12 Company-University Collaborations (Licensing/Partnering) Analysis
13 Epilepsy Key Companies
14 Epilepsy Key Products
15 Epilepsy- Unmet Needs
16 Epilepsy- Market Drivers and Barriers
17 Epilepsy- Future Perspectives and Conclusion
18 Epilepsy Analyst Views
19 Appendix
20 About DelveInsight

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